Bioproduction of citric acid exposed to some coumarins

The global citric acid market size was valued at USD 2909-59 million in 2021 and is experted to expand at a CAGR of 4.63% during the forecast period reaching USD 3818.2 million by 2027. The efficacy of 7-hydroxy-3-methyl-4-phenyl coumarin on microbial bioproduction of citric acid by Aspergillus fumigatus AR - 902, Aspergillus parasiticus AR- 904, Aspergillus awamori AR - 861 Aspergillus oryaze AR - 962 and Aspergillus niger AR- 953 has been assessed. It has been observed that the fungal strain Aspergillus niger AR - 953 has been found most potential and effective for the citric acid fermentation process. It has been found that the micelles, i.e., sodium hexadecyl sulfate at molar concentration, i.e.,6.0 × 10-5M has stimulatory effect on production of citric acid by Aspergillus niger AR - 953 and enhances the yield of citric acid to an extent of 13.962% higher in comparison to control fermentor flasks, i.e., 4.366 g/100 mL under the optimized conditions, viz. 330C temperature, 1.8 pH, 11 days of incubation period with 30% (w/v) molasses solution.